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Medications Predisposing to Heat Illness

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Medications Predisposing to Heat Illness, Drugs Predisposing to Heat Illness

  • See Also
  1. Heat Illness
  2. Heat Illness Risk Factors
  1. See Recreational and Illicit Drugs below
  2. Dextroamphetamine (e.g. Adderall) and Lisdexamfetamine (Vyvanse)
  3. Epinephrine
  4. Ephedrine
  5. Ephedra-containing supplements
  6. Norepinephrine
  7. Decongestants
  1. Atropine
  2. Scopolamine
  3. Benztropine Mesylate
  4. Antihistamines
  • Causes
  • Neurologic and psychiatric agents
  1. Antiparkinsonism Medications
  2. Antipsychotics (disrupted hypothalamic Thermoregulation)
    1. Butyrophenones (e.g. Haloperidol)
    2. Clozapine
    3. Olanzapine
    4. Quetiapine
  3. Tricyclic Antidepressant
    1. Amitriptyline (Elavil)
    2. Imipramine
    3. Nortriptyline
    4. Protriptyline
  4. Monoamine Oxidase Inhibitors
    1. Phenelzine
    2. Tranylcypromine
  5. Miscellaneous psychiatric agents
    1. Selective Serotonin Reuptake Inhibitors (SSRI)
    2. Lithium
  6. Neuroleptics
    1. Gabapentin
    2. Lamotrigine
    3. Topiramate
  • Causes
  • Cardiovascular
  1. Beta Blockers
  2. Calcium Channel Blockers
  3. Diuretics
    1. Caffeine
    2. Alcohol
    3. Furosemide (Lasix)
    4. Hydrochlorothiazide
    5. Bumetanide (Bumex)
  1. Prochlorperazine
  2. Chlorpromazine hydrochloride
  3. Promethazine hydrochloride
  • Causes
  • Other Medications
  1. Laxatives
  2. Thyroid receptor Agonists (e.g. Levothyroxine)
  3. Salicylates (e.g. Aspirin) and other antiplatelet agents (e.g. Clopidogrel)
  1. Caffeine
  2. Nicotine products (e.g. Cigarettes, cigars, Vaping products)
  3. Alcohol
  4. Lysergic Acid Diethylamide (LSD)
  5. Phencyclidine (PCP)
  6. Methamphetamine and other illicit Amphetamines (e.g. MDMA)
  7. Ephedra-containing supplements
  8. Cocaine
  9. Bath Salts
  10. Ecstacy
  11. Jimson Weed
  12. Hallucinogenic Mushrooms
  • References
  1. Salinas and Ruttan (2017) Crit Dec Emerg Med 31(9): 3-10
  2. Gauer (2026) Am Fam Physician 113(4): 369-81 [PubMed]
  3. Pryor (2015) Wilderness Environ Med 26(4 suppl):569-75 [PubMed]